Most info comes from
Dudai. Italicized text was taken from Schacter. Italicized and underlined
text come from MacPhail.
I. Go over syllabus
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Grading
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A >89.99
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B 80-89.99
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C 70-79.99
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Recieve credit for participation, presentation, journal, quizzes and final
exam. Weighting of each portion is outlined in syllabus.
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Readings - outlined in syllabus (required & optional), some handouts
may be added to the required reading list at a later date.
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Due dates for various assignments
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Study guide.
II. Student background. What they expect.
III. Defining learning and memory?
The subject of Learning & Memory has been investigated by many
different branches of science. Thus, we encounter a problem right
from the start. This is a problem of semantics. Scientist from different
fields have a different bias and vocabulary. For instance Behaviorist
talk about adaptive changes in behavior, computer scientist discuss storage
and output etc. Cognitive psychologists discuss internal representations
or schemas. Because of all of these different approaches we need
to come to some concensus. The definition that we will use to guide our
discussion this semester is as follows.
Learning is the process by which relatively permanent
changes occur in behavioral potential, as a result of experience.
Memory is the relatively permanent record of the experience
that underlies learning.
As a simple summary that encompasses all disciplines we can say that
learning is a process while memory is the product
of that process.
relatively permanent- days, weeks, months, years
behavioral potential - means that the probablility of a given behavior
occurring has changed. * eg.arm radial maze animals may choose different
arms based on previous experience.
*in these definitions we've eliminated the term adaptive because the change
in behavioral potential that is produced by learning does not necessarily
facilitates survival. Some debilitating diseases whose manifestation can
be explained using theories of learning. eg Obsessive/Compulsive disorders
Since I am a neuroscientist I will take our definition one step further
by pointing out that because behavior is a function of activity in the
central nervous system, learning is the production of relatively permanent
changes in the central nervous system, as a result of internal and external
stimuli.
Compare to above definition of learning.
IV. How is this process studies? Levels and approaches to studying
L& M. Alluded to this idea of different approaches in previous
section.
A. At various levels
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Behaving organism - phenomenological -
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Neuronal Systems (Dudai 'organ level'): - input - output or stimulus
- response characteristics
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Circuit (Dudai 'suborgan level'): how does the different areas of
the brain function as an integrated organ
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Cellular: individual neurons and their connections
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Molecular: biochemical biophysical events
B. Various approaches:
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Some researchers feel that the behaving organism is where one should start
and move from there to the molecular. eg NMR This approach is referred
to as the top- down approach. This approach is espoused by
the Schacter text. Places heavy emphasis on reported memories which leads
to the inevitable question of whether the retrieval process or the storage
process is to blame for unrealistic memories. but that is a story we will
get to soon.
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Some researchers feel that complex 'internal representations' or memories
are the manifestation of interactions between processes that are fundamental
and thus are found throughout the animal kingdom. These researchers thus
study the molecular level and extrapolate to the behaving organism. This
approach is a bottom-up approach.this approach is espoused
by Dudai.
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The rationales for using this approach are numerous
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Simple systems are expected to be more amenble to experimental analysis
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Ample information is available on cellular and molecular processes in general,
and experimental techniques for their analysis are highly developed.
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Simple systems and cellular studies may reveal universal components of
the learning process.
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Caveats
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The same mechanisms revealed in the simple systems may not be pertinent
in more complex systems.
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Even if the small cellular/molecular systems apply in complex organisms
they in and of themselves do not explain complex behavior.
This course will be structured in the following manner. First we
will look at the study of L&M from a historical
perspective. We will then investigate different learning paradigms
from a behavioral, cellular and finally molecular perspective. A
useful framework can formed by placing the
learning paradigms along the top of a table and the different levels of
investigating the phenomenon along the left margin of the same table.
As we move through the semester the intersections of these headings will
eventually be filled in.